The cell- and tissue-specific operation of estrogens as well as their receptors provide healthy aging as well as conflicting outcomes from estrogen therapy in diseases that are related to aging [7]
[Google Scholar] 59.Kypridemos C., Guzman-Castillo M., Hyseni L., Hickey G.L., Bandosz P., Buchan I., Capewell S., OFlaherty M
(PubMed) van Wijngaarden JP, Doets EL, Szczecinska A, et al
Cell 59 , 21012117 (2024)
In the following sections, we will delineate the expression profiles and functional mechanisms of the Vitamin DVDR signaling axis distinct cutaneous cell types, thereby revealing its diverse biological roles in maintaining skin homeostasis and responding to aging-related stressors
Researchers have gradually explored its function in different endocrine and physiological roles