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IL-10 acts as a major inhibitor of proinflammatory cytokines, such as IL-2 , TNF- , and CCL2 , while promoting anti-inflammatory factors like TGF- and nerve growth factors [23]

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Clinical trials such as SURPASS have demonstrated Tirzepatides ability to significantly reduce HbA1c levels (a marker of long-term blood glucose control) and induce substantial weight loss in patients with type 2 diabetes

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