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It has been shown that GLP-1RA semaglutide can improve working and spatial memory in transgenic AD modelling APP/PS1/tau (3xTg) mice, promote the release of anti-inflammatory factors and inhibit the production of pro-inflammatory factors in the cerebral cortex and hippocampus, as well as reduce the deposition of -amyloid in the CA1 subfield of the hippocampus

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An acyl-ghrelin-specific neutralizing antibody inhibits the acute ghrelin-mediated orexigenic effects in mice

576,577 Superoxide dismutase (SOD) was the first antioxidant enzyme discovered and remains the only enzyme known to eliminate superoxide anion (O 2 ) in mammals, playing a crucial role in combating oxidative stress