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Relationship between mirna and ferroptosis in tumors

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The role of NCOA4 in ferroptosis was determined by silencing the expression of NCOA4 by siRNA lentiviral transfection, and the result shows that an iron chelator-like effect was produced in the NCOA4-deficient KGN after ferric citrate (FAC) intervention (Fig

Mutual regulation of metabolic processes and proinflammatory NF-B signaling

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In a similar fashion, the expression of nuclear oxidized proteins was higher when the nuclear GSH was depleted with DEM, with a striking difference at 6 hours of culture, when the nuclear GSH level in these cells was lowest