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Ohara T, Muroyama K, Yamamoto Y, Murosaki S (2016) Oral intake of a combination of glucosyl hesperidin and caffeine elicits an anti-obesity effect in healthy, moderately obese subjects: a randomized double-blind placebo-controlled trial
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and down-regulation of lactate dehydrogenase (LDH), Fe 2+ , malondialdehyde (MDA), and ROS 512
The Surmount 1 study protocol that participants followed was not high protein low carb - but is instead balanced and based on eating 500 calories a day fewer than our body needs to remain at the same weight
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