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When BPC-157 (0.0045 mg/lb or 0.0000045 mg/lb) was co-administered, tolerance development was prevented

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Only total GSH (free, oxidized, and protein-bound fractions combined) was elevated in plasma following SAG dosing, at levels significantly higher than after equivalent oral L-GSH dosing

The authors found that garlic preparations significantly lowered total cholesterol and low-density lipoprotein (LDL)-cholesterol compared to placebo

This approach emerged pragmatically from research schedules but aligns well with receptor recovery kinetics and avoids the potential tolerance development that continuous daily dosing over many weeks might produce

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