When combined dexamethasone and vitamin B12 was administered, upregulation of brain-derived neurotrophic factor (BDNF), glial cellderived neurotrophic factor, NT-3, and IL-6 were found in a rat sciatic nerve injury model 19
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Theyve also seen decreases in blood glucose levels, blood pressure, and cholesterol
Borderline results may warrant additional testing (methylmalonic acid or homocysteine)
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Gentle mixing by rolling the vial between the hands may be appropriate if settling has occurred, but aggressive agitation should be avoided