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Drink at least two litres of water a day Avoid alcohol for at least 24 hours before and after treatment Limit alcohol and caffeine intake Avoid strenuous exercise for 48 hours post-treatment No sunbeds for one week

Small sample sizes : Many studies involve fewer than 100 participants, limiting statistical power

Due to natural variations in properties of active ingredients, the product color, taste and smell may vary slightly from batch to batch

K., & Maity, C

All animals received one 90 L gavage per day for 5 days between D-2 and D2 containing 100 mg/kg phenformin or sterile water, as indicated in each case