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The sensitivity analysis was used to identify the dependence of overall effect size on a single study

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Indeed, in experimental models, butyrate treatment has been shown to induce autophagy and improve clearance of misfolded proteins, as well as improve synaptic and cognitive function in mice with neurodegenerative pathology [56]

found that SIRT2, rather than SIRT1, regulates the acetylation levels and activities of glycolytic enzymes (ALDOA, PGK1, ENO1, and GAPDH), highlighting the crucial role of SIRT2 in the glycolytic pathway