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Additionally, the chimeric peptides demonstrated enhanced skin adsorption and penetration, excellent biocompatibility, and effectively facilitated in vivo wound healing

BPC-157 demonstrates exceptional safety in animal toxicology studies, with comprehensive evaluations in mice, rats, rabbits, and dogs failing to establish a lethal dose (LD) across wide dose ranges extending from standard research doses (6 g/kg) to levels exceeding 1000-fold higher concentrations (20 mg/kg), with no evidence of acute toxicity, organ-specific damage, or systemic adverse effects even following repeated high-dose administration

Dodda JM, Deshmukh K, Bezuidenhout D, Yeh Y-C

Acknowledgements The study is supported by a Singapore EDB-IPP grant (grant number: RL2012035)