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For the CAS site, there is high homology between tryptophan and tyrosine residues across the six AChEs, except for Tc AChE, which contains a phenylalanine instead of a tyrosine

Contact an eye care provider immediately if you experience: Sudden vision loss in one or both eyes A dark, missing or blank area in your field of vision Sudden changes in color vision New flashes of light or a sudden increase in floaters Vision changes that are severe or continue to worsen Sudden vision loss is a medical emergency and should be evaluated as quickly as possible

Your provider may slow your dose escalation, recommend hydration adjustments, or switch your formulation instead of discontinuing therapy

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