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Physiological fatigue corresponds to a homeostatic process, selected by evolution for its usefulness, whereas pathological fatigue unravels a dyshomeostatic state, which reflects a combined dysfunctioning of numerous potential systems, revealed by both physiological issues (chronic inflammation, mitochondrial dysfunctioning, cardio-pulmonary pathologies, endocrinopathies, vitamin deficiencies) and interoceptive processes, with inappropriate corrections by the brain of biological perturbations

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That shift not any kind of bleaching action is the real biology behind "glutathione for brighter skin." It's a gradual change in the type of pigment your skin produces, not a chemical strip of the pigment you already have

Participants in trials often notice that their skin feels firmer and bouncier, with a reduction in that crepey look on thinning aged skin