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SLC1A5 is a crucial sodium-dependent solute carrier protein that facilitates the import of glutamine and serves as the principal conduit through which cancer cells acquire glutamine [189, 190]

Willards team, in JCI Insight, calls it a biased, imbalanced agonist, which is a fancy way of saying it leans on the GIP receptor while behaving like a plain GLP-1 copy at the GLP-1 receptor

In June 2023, The FDA granted fast track designation to efinopegdutide for the treatment of NASH

J Biol Chem 1992;267:7402-5.ArticlePubMed 16

The pen should be discarded 56 days after starting use, even if there is some medication remaining

However, nearly 25% discontinued dulaglutide by the end of the study