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3 The authors explain that the bumps, even though they are pigmented, can probably be recognized in childhood or at birth, and no treatment is needed

Thus, our data indicate that paraxanthine increases BDNF levels to a greater extent than caffeine, which may underlie its cognitive-enhancing effects in both young and old animals

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The compound works by activating an enzyme called AMP-activated protein kinase (AMPK), often referred to as a "metabolic master switch" that helps regulate energy balance at the cellular level