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Without robust clinical trials in breastfeeding populations, conservative medical practice recommends avoiding GLP-1 medications during active nursing, particularly during the first 6 months when infants are most vulnerable to systemic drug exposure

They may increase the dose beyond what would be appropriate, creating the overdose scenario described above

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Duan L, Rao X, Braunstein Z, Toomey AC, Zhong J

El-Moslemany RM, El-Kamel AH, Allam EA, Khalifa HM, Hussein A, Ashour AA

That entire pathway has to work