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Essential for the synthesis of collagen, the main structural protein found in connective tissue

Bone health should be considered during significant weight loss, particularly in older adults or those with osteoporosis risk factors

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A good example is a review published in 2003 in Endocrine Reviews , in which the authors note the importance of [growth hormone] and IGF systems in normal skin homeostasis. They specifically mention the role that growth hormone plays in collagen synthesis and the effect that IGF has on skin cell proliferation