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In fact, although the BBB is disrupted at the tumor core, it remains largely intact in infiltrated brain regions, limiting systemic drug access to invasive GBM cells that drive recurrence after surgical resection (17)

however, these findings were primarily derived from experiments in rodent models, which limits their immediate translational impact (Wong et al., 2014)

The fate of the luminal GSSG generated is unclear

These vitamins are water-soluble, meaning they dissolve in water and are not stored in the body, necessitating regular intake through diet or supplementation

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