Accession numbers Accession numbers and sequence information of the genes investigated in this study can be found in the S
Other medicines warranting caution include: Oral contraceptives the tirzepatide SmPC (Mounjaro, MHRA/emc) notes a reduction in oral contraceptive exposure during initiation and dose escalation, and advises considering additional contraceptive precautions during this period
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All reviewed articles comprised of both randomised and non-randomised intervention studies
Building on these findings, our recent study demonstrated that sulforaphane prevented ASD-associated phenotypes induced by valproic acid, including oxidative stress, synaptic loss and neural activity disruption, highlighting sulforaphanes potential as a preventative strategy against early life ASD risk (Bessetti et al., 2025)
Certain stress pathways including endoplasmic reticulum stress and the integrated stress response inhibit cap-dependent translation through inhibitory phosphorylation of the initiation factor eIF2