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Both classes of drugs slow disease progression and help prevent complications

Vit-Es antioxidant properties combat ROS and reduce MDA, with various studies indicating a correlation between OSMs, including MDA, and the severity of IBD (206)

Hypoxia-inducible factor 2-alpha-dependent induction of amphiregulin dampens myocardial ischemia-reperfusion injury

Tesamorelin is a GHRH analog that stimulates pituitary growth hormone release

While there is no incidence data specific to cholestatic DILI, a figure of 1.47 per 300,000 can be extrapolated from data reported by Bjrnsson et al

If microbial shifts partially mediate metabolic benefits, combination strategies could become more common