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J Physiol 591(17):40874097
In short, while B12 corrects deficiency reliably, it does not act like a weight-loss drug in people with normal levels
Thus, an optimal flow velocity range of 400600 m/s has been found to favor both tumor cell arrest within vascular regions and endothelial remodelling, leading to extravasation and metastasis [229]
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Further, animal studies indicate that it may strengthen the gut-brain axis, improving feedback between the GI tract and the central nervous system to elicit systemic effects [2, 4, 11]
By activating these receptor systems, researchers can investigate mechanisms involved in satiety signaling and metabolic regulation
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