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Conversely, no significant changes were seen in FSH, LH, or estradiol across the study period, suggesting that the primary hormonal effects of the intervention were centered on IGF-1 and testosterone [2]

In pre-clinical research, DSIP is often used to examine neurotransmitter interaction, sleep-cycle signaling markers, and stress-response modulation pathways

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This has been addressed through the use of multimodal intravital microscopy of deformable and adjustable in size fluorescently-labelled polyacrylamide beads that allow spatiotemporal measurements of solid stress applied to relatively small animal tumors in vivo [116]