Groups at higher risk of deficiency include older adults (due to reduced stomach acid production), vegans and vegetarians, people with pernicious anaemia or gastrointestinal disorders affecting absorption, and those taking certain medications such as metformin or proton pump inhibitors
Shi H, Zheng Y, Zhao J, Li Y, Jia H, Hou X, Li Y, Li J, Wu C, Gao L (2023) Zexie decoction reduce glucose-dependent lipid accumulation and oxidative stress in Caenorhabditis elegans
While in vitro systems reveal molecular and cellular responses, in vivo models further contribute to the understanding of biodistribution, accumulation, and systemic effects (Fig
We look forward to working with Ascendis to explore the potential of the TransCon technology platform to reduce the dosing frequency of GLP-1 receptor agonists and other treatments for cardiometabolic diseases. GLP-1 treatments are a class of diabetes and obesity medications that mimic a hormone that regulates blood sugar and suppresses appetite
10.1006/frne.2001.0224 38 HajnalA.ZharikovA.PolstonJ
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