Research has shown that drugs such as atglistatin (131), puerarin (132), nuciferine (133) and formononetin (134) improve the related diseases by inhibiting fat lipolysis through ATGL and HSL (135138), as detailed in Table 2
High Uric Acid Induces Insulin Resistance in Cardiomyocytes In Vitro and In Vivo
10.1113/jphysiol.2006.112896 121 TopolnikL.CamirO
Clinical trials have shown that these medications reduce the risk of major cardiovascular events, including heart attack and stroke
Key Regulatory Points as of 2026: Not FDA-approved for any medical indication Cannot legally be sold as a drug, food, or dietary supplement for human consumption Legally sold as a "research chemical," not intended for human use Not a DEA-scheduled substance, so possession is not illegal (unlike anabolic steroids) Many medical clinics offer BPC-157 treatments despite lack of approval The FDA has expressed safety concerns due to the lack of human clinical trial data and the potential for adverse effects from unregulated manufacturing
[4] Ballatori N, Krance SM, Notenboom S, et al