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Overall, these results indicate that CERT1 degradation involves the proteasome and that the contribution of autophagy is negligible

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Additionally, the study showed VK2735 treatment to be safe and well tolerated with the majority of treatment emergent adverse events (TEAEs) being categorized as mild or moderate

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Evidence from animal models suggest that improvements in spatial memory following an acute bout of resistance exercise may be mediated via IGF-1, however the relationship between IGF-1 and short term cognitive performance in humans remains unclear (Cassilhas et al., 2012)