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However, GPNAs high toxicity of GPNA limits its use in cellular experiments, and the mechanism of V-9302 inhibition is controversial and requires further investigation [80]

Caveats: Neither test is FDA-cleared as diagnostic for HPA disorders

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Many patients have taken these medications for years, often at higher doses, and new concerns are emerging about chronic gastrointestinal, neurological, pancreatic, renal, and hormonal effects

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