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Although regulators reviewed data from more than 90 clinical trials involving over 100,000 patients and found no statistically significant increase in suicidal thoughts compared to placebo, critics argue the decision comes too soon

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Why GIP Was Initially Controversial Early studies in people with type 2 diabetes found that their insulin response to GIP was diminished compared to people without diabetes

A mild fullness lasted about 90 minutes

Nausea or constipation that persists is something to raise with the prescriber

However, this inhibitory effect is significantly weakened in patients with T2DM, indicating that its potential application in diabetes treatment requires further investigation