Fat acts as a thermal buffer, and as your stores shrink, you may feel the cold more intensely, especially in your hands, feet, and face
Beyond central nervous system trauma it has also been examined in models of peripheral nerve injury
10.1016/j.regpep.2009.05.008 6 BarisicI.BalenovicD.KlicekR.RadicB.NikitovicB.DrmicD.et al (2013)
EGR-1 transcription factor activation: BPC-157 activates early growth response protein 1 (EGR-1), a transcription factor that regulates the expression of multiple growth factors essential for intestinal repair, including platelet-derived growth factor (PDGF) and fibroblast growth factor (FGF)
It randomised 156 participants with early disease to daily subcutaneous lixisenatide or placebo for 12 months, followed by a 2-month washout
The entry site for glenohumeral injection, however, is a little lower, and the direction different