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For therapeutic correction of deficiency , particularly in cases of pernicious anaemia or malabsorption, hydroxocobalamin injections are considered most effective in UK clinical practice

Side effects are rare, but some individuals may experience mild digestive discomfort, such as bloating or nausea, especially if taken in excess

To confirm diabetes induction in rats, 72 h after STZ injection, we measured blood glucose, using a glucometer instrument (Easy Gluco, Korea)

Table 1 summarized the clinical trials of metformin and TZDs on cognition, MCI, AD, and PD