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It is primarily found in your muscles and liver

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1998 Jun;18(6):407-30

They interact with cellular signalling pathways, modulate inflammation, influence gene expression, and communicate with the gut microbiome

These medicines are typically considered when metformin and other therapies have not achieved adequate glycaemic control, or when certain patient characteristics make them particularly suitablefor example, where weight loss is beneficial or cardiovascular or renal protection is a priority

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