Dihydroergotamine has also been shown to be an inhibitor of cytochrome P450 3A catalyzed reactions and rare reports of ergotism have been obtained from patients treated with dihydroergotamine and macrolide antibiotics (e.g., troleandomycin, clarithromycin, erythromycin), and in patients treated with dihydroergotamine and protease inhibitors (e.g., ritonavir), presumably due to inhibition of cytochrome P450 3A metabolism of ergotamine (see CONTRAINDICATIONS)
Good news for couples trying to conceive: studies have found that tomato consumption may help address several factors behind male infertility
this could improve tolerability and, therefore, have a positive impact on quality of life as side effects such as fatigue, headaches, or dizziness associated with treatment become less frequent
Generally, GSH binding shows relatively strong affinity to the G-site (near the active cysteine residue) and weak affinity to the H-site in the case of WT proteins
In: Howard R, Kullmann D, Werring D, Zandi M (eds) Neurology: A Queen Square Textbook, 3rd edn
however, an analysis of the cargo release data reveals that the reduction of prodrugs does not fully translate into the corresponding cargoes, as evidenced by the fact that the percentage decrease in prodrugs exceeds the percentage of cargo released
