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Intramuscular (IM) injections are typically administered into the arm's deltoid muscle, the vastus lateralis muscle of the thigh, or the ventrolateral muscle of the hip

This triggers the MAPK cascade, such that Ras-GTP activates Raf [also called MAPK kinase kinase (MAPKKK)], which in turn activates MEK1/2 [MAPK kinase (MAPKK)]

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Bronchoscopy with epithelial brushings and BAL were performed as previously described (6, 43, 44)

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