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(2011 ) (17,20E)-17,20-[(1-methoxyethylidene)bis(oxy)]-3-oxo-19-norpregna-4,20-diene-21-carboxylic acid methyl ester (YK11) is a partial agonist of the androgen receptor

The benefits exceed what would be expected from glucose control alone, suggesting direct protective effects beyond metabolic improvement

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These trials represent studies specifically designed to assess the efficacy and safety of TZP in obesity management