How does this have to do with GLP-1s
For a drug to passively diffuse through this layer, it typically needs to be: Small in molecular size Lipophilic (fat-soluble) However, GLP-1 molecules: Are too large and hydrophilic Cannot naturally penetrate the skin barrier Even if GLP-1 patches claim to have GLP-1 drugs, the molecules cannot pass through the skin barrier without support
Systematic reviews and meta-analyses suggest modest benefits for glycaemic control and lipid profiles in people with type 2 diabetes or metabolic syndrome, but the overall quality of evidence is considered moderate at best
Errors in BMI, lab values, diagnoses, or medication history can easily trigger a denial
Idris, I., Abdulla, H., Tilbrook, S., Dean, R
Lancet Neurol