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The activation is linked to the generation of vasoconstrictive agents, including MCP-1, (pro)renin receptor, endothelin, and angiotensin II, while concomitantly diminishing vasodilatory compounds like nitric oxide, which may contribute to the development of hypertension and lead to decreased viability of cardiomyocytes and myocardial damage

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[DOI] [PMC free article] [PubMed] [Google Scholar] 79.Pilon-Smits E.H.A

To view a copy of this licence, visit About this article Cite this article Bachhar, A., Johannson, G., Sahin, M