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Once absorbed into the bloodstream, NAC is quickly hydrolyzed into active cysteine, which then pairs with circulating glycine to actively synthesize glutathione inside the cells

POTS and Orthostatic Intolerance: By facilitating the livers clearance of circulating histamine, glutathione reduces inappropriate vasodilation and blood pooling, helping to stabilize blood pressure and reduce the compensatory rapid heart rate associated with dysautonomia