Given the reduced glutamine levels observed in the MMA group, lower NAAD may reflect impaired glutamine-dependent NAD + synthesis rather than a primary defect in NAD metabolism
Klopstock T, Naumann M, Seibel P, Shalke B, Reiners K, Reichmann H
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[ii] Sackmann-Sala, L., Ding, J., Frohman, L