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10.1016/j.regpep.2009.11.005 39 GojkovicS.KrezicI.VrdoljakB.MalekinusicD.BarisicI.PetrovicA.et al (2020)

The clinical rationale for the stack is strongest in cases of significant injury: post-surgical recovery, chronic multi-site presentations, and cases where conservative treatment approaches have not produced adequate progress

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Plasma exchange (plasmapheresis) is the treatment for TTP and HUS

However, it does not guarantee a zero BAC or eliminate the effects of alcohol entirely