which semaglutide is most effective vs. Tirzepatide: What's the Difference and Right for You?: Envizion Medical: Wellness Center Best Time to Take Semaglutide:

These compounds may increase inflammatory signaling, glutathione demand and liver workload

Bax activation and stress-induced apoptosis delayed by the accumulation of cholesterol in mitochondrial membranes

Immunity 2021;54:253146.e5

This is why combining medication with lasting behaviour changesuch as through coaching or resilience trainingis key to long-term success

Insulin signaling directly influences immune cell metabolism, macrophage polarization, and T-cell differentiation, thereby shaping inflammatory responses within musculoskeletal tissues (27)

If youre on any of these, that doesnt mean Zepbound cant work for you, but it does mean your provider should factor them into your treatment plan