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Two full doses within days of each other dramatically increases drug levels and can cause severe nausea, vomiting, and gastrointestinal distress

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GLP-1RAs and osteoclasts The greater degree of bone degradation observed in mice lacking GLP-1R indicates that GLP-1R signaling suppresses osteoclast differentiation and bone resorption

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SCREENING FOR DIABETES MELLITUS Strict glucose control is implemented to prevent microvascular and macrovascular complications in patients with diabetes (RCT, General) [8-10]