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The article says GLP-1 treatment is generally appropriate for adults with a BMI of 30 or higher, or 27 or higher when weight-related comorbidities such as type 2 diabetes, hypertension, sleep apnea, or cardiovascular disease are present

doi: 10.1038/372475a0 209 PatelA.LeeH

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Structural mechanisms in NLR inflammasome signaling