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Together, these findings suggest that age-dependent decrease in BDNF signaling may cause synaptic alterations through an initial and preferential effect on GABA presynaptic genes

Semaglutide reduces stomach acid production as a secondary effect of delayed gastric emptying

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Supporting this, VDR knockout models exhibit impaired folliculogenesis and anovulation, suggesting the significant role of vitamin D in modulating follicular maturation and luteinization (102)