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This is a normal physiological response, not a sign that your injection or oral medication has become ineffective

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Diminished CFTR expression has been observed in spermatozoa from men with various sperm quality abnormalities (teratozoospermia, asthenozoospermia and oligozoospermia), and correlates positively with sperm motility and morphology

Retatrutide is initiated at a low dose and gradually increased over several months to minimise gastrointestinal side effects such as nausea, vomiting, and diarrhoea