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These medications work by mimicking naturally occurring intestinal hormones that regulate blood glucose and appetite

It is a dual agonist that targets both the GLP-1 (glucagon-like peptide-1) and the amylin receptor, which helps to regulate appetite and glucose metabolism

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Biochemistry 44, 64636470

According to FDA labeling, no clinically meaningful differences in tirzepatide pharmacokinetics have been observed across all levels of renal function, including severe renal impairment and end-stage renal disease

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