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EGCG can inhibit Th1 cell polarization, while hyperoside can regulate the Th17/Treg balance, hesperidin helping rebalancing Th1/Th2 and Th17/Treg, and wogonin has been found to activate the AhR pathway, thereby preventing ILC3 from transforming into ILC1 (160163)

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Side effects typically improve over time with both medications