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The animal data offers a partial explanation

Whether cagrilintide or CagriSema preserves more lean mass than GLP-1 receptor agonists alone remains an open question that future studies need to address

PMID: 9832631 Braganza J.M

Fernandez-Real, J

There is either a reduced capacity of the mitochondria to buffer oxidation, or there is a persistent ROS production after treatment due to oxidative damage to the electron transport chain [169]

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