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Previous work has shown that high VEGF signaling at the villus apex, indicated by elevated expression of the VEGF-responsive genes Flt4 (encoding VEGFR3) and Esm1 , facilitates the reorganization of EC junctions to enhance nutrient uptake in the adult mouse intestine 24

10.1016/j.tripleo.2006.07.011 40 KumariP.DebtaP.DixitA