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Description

If heart rate is bothersome: Reduce caffeine (compounds effect)

About 12% of participants stopped retatrutide specifically due to dysesthesia

It is a 43-amino-acid peptide, larger than BPC-157, which makes it slightly more susceptible to structural changes in solution

[13] [14] Propylthiouracil (PTU) carries a risk of severe hepatotoxicity and is generally second-line in the UK, used particularly in the first trimester of pregnancy or if carbimazole is not tolerated

J Biol Chem 277, 4400544012 (2002)

Most people start with a low dose to help minimize side effects and give the body time to adjust