A method for preventing radiation-induced ototoxicity in an individual in need thereof comprising intratympanic administration of a pharmaceutical composition comprising a therapeutic agent selected from a JNK inhibitor, TRPV modulator, an MET channel inhibitor, and an otoprotectant to the individual in need thereof, wherein the pharmaceutical composition is administered prior to onset of radiation therapy, and wherein the composition provides sustained release of the therapeutic agent into the ear for a period of at least 5 days after a single administration
Vitamins C and E (155, 156), N-acetyl cysteine (NAC) (112, 157), resveratrol (58162), and melatonin (163166) have variously been shown to reduce the numbers and sizes of endometrotic implants in animal studies
Luteolin attenuates hypertension via inhibiting NF-B-mediated inflammation and PI3K/Akt signaling pathway in the hypothalamic paraventricular nucleus
Other negative physical effects of smoking marijuana include dry mouth and throat, an increased resting heart rate, and the expansion of both lung passageways and blood vessels
But it's also more expensive and can cause more side effects
Neuroprotective effects of GLP-1R agonists GLP-1 and its mimetics can cross the BBB, therefore, are able to affect the CNS function such as cognition and neuroprotection (138)
