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It is commonly used to treat type 2 diabetes but has also been found to have beneficial effects on weight loss

doi: 10.1016/j.lungcan.2011.11.012

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Pouwer F, Snoek FJ, van der Ploeg HM, Adr HJ, Heine RJ (2001) Monitoring of psychological well-being in outpatients with diabetes: effects on mood, HbA 1c , and the patients evaluation of the quality of diabetes care: a randomized controlled trial

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Losing it lowers your resting metabolic rate, which makes long-term weight maintenance harder once you eventually taper off or stop the medication