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GLP-1 users often become mildly dehydrated due to reduced food and fluid intake, nausea, and changes in appetite that cause them to forget to drink

This flushes metabolic waste from the periphery, creating the pressure gradient required for the brains glymphatic system to drain toxic proteins

Timing Optional Marker Homocysteine Why it matters Adds methylation and cardiovascular context when B-vitamin status is being reviewed

Low testosterone levels can lead to fatigue, weight gain, and a decline in overall well-being

But because glutathione helps recycle other antioxidants like vitamin C and vitamin E, it frees them up to be re-used to remove free radicals and decrease oxidative stress

Retatrutide has not yet completed a dedicated cardiovascular outcomes trial